Emerging Therapies for Rheumatoid Arthritis
نویسندگان
چکیده
منابع مشابه
Emerging Therapies for Rheumatoid Arthritis
Diverse strategies to develop novel treatments for rheumatoid arthritis which specifically target those patients who do not respond to available medications, including biologics, are currently being explored. New potential therapeutic approaches which may become available as part of standard therapeutic regimens include the propagation of regulatory T cells and-in the future-of regulatory B cel...
متن کاملNew and emerging therapies for the treatment of rheumatoid arthritis
The introduction of tumor necrosis factor (TNF) inhibitors in the late 1990s significantly changed the therapeutic approach for rheumatoid arthritis (RA). With the approval of subsequent TNF inhibitors as well as other biologic agents effective in the management of RA, the treatment paradigm has become increasingly complex. This review examines the current literature regarding the efficacy and ...
متن کاملEmerging biologic therapies in rheumatoid arthritis: cell targets and cytokines.
PURPOSE OF REVIEW Biologic therapy for rheumatoid arthritis targets specific molecules, both cell-bound and soluble, that mediate and sustain the clinical manifestations of this complex disease. The aim of all the therapeutic strategies is to achieve complete and sustained suppression of inflammation, in the absence of unacceptable short-term and long-term toxicity. Despite the success of the c...
متن کاملImmunological therapies for rheumatoid arthritis.
Rheumatoid arthritis (RA) is a chronic inflammatory arthritis of the synovial joints that causes loss of function and a shortened life expectancy. In the last 10 years there have been major advances in the treatment of RA, including more aggressive use of disease-modifying anti-rheumatic drugs and the development of immune therapies targeted to molecules and cells important in the immunopathoge...
متن کاملEmerging Treatments for Rheumatoid Arthritis:
Early treatment with disease-modifying anti-rheumatic drugs (DMARDs)--alone or in combination-can prevent joint damage and minimize disability. Until recently, the DMARDs used predominantly in patients with rheumatoid arthritis had been methotrexate, sulfasalazine, and hydoxychloroquine. Older DMARDs such as gold, d-penicillamine, and azathioprine have fallen out of favor because of their longt...
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ژورنال
عنوان ژورنال: Rheumatology and Therapy
سال: 2016
ISSN: 2198-6576,2198-6584
DOI: 10.1007/s40744-016-0032-4